ERK and p38 MAPK Signaling Pathways Negatively Regulate CIITA Gene Expression in Dendritic Cells and Macrophages

Dendritic Cells and Macrophages Negatively Regulate CIITA Gene Expression ERK and p38 MAPK Signaling Pathways

The p38 MAPK, CaMK and calcineurin-mediated signaling pathways transcriptionally regulate myogenin expression

1. Department of Biochemistry, Hong Kong University of science & Technology, Clear Water Bay, Kowloon, Hong Kong, Peoples Republic of China. 2. School and Department of medicine, University of California, San Diego, La Jolla, CA 92095, USA. 3. Department of Oncology, University of Western Ontario, London, Ontario, Canada N6A, 4L6. 4. Molecular Oncology Group, Department of Medicine, McGill Univ...

Role of regulatory elements and the MAPK/ERK or p38 MAPK pathways for activation of human cytomegalovirus gene expression.

A series of recombinant viruses with either site-specific mutations or various deletions of the early UL4 promoter of human cytomegalovirus were used to determine the roles of regulatory elements and the effects of the mitogen-activated protein kinase (MAPK) pathways. Viral gene expression was regulated by upstream cis-acting sites and by basic promoter elements that respond to the MAPK signal ...

Hesperetin Inhibits Vascular Formation by Suppressing of the PI3K/AKT, ERK, and p38 MAPK Signaling Pathways

Hesperetin has been shown to possess a potential anti-angiogenic effect, including vascular formation by endothelial cells. However, the mechanisms underlying the potential anti-angiogenic activity of hesperetin are not fully understood. In the present study, we evaluated whether hesperetin has anti-angiogenic effects in human umbilical vascular endothelial cells (HUVECs). HUVECs were treated w...

All-trans Retinoic Acid Regulates the Balance of Treg-Th17 Cells through ERK and P38 Signaling Pathway